Ident and Sim

Format Conversion

-Combine FASTA
-EMBL to FASTA
-EMBL Feature Extractor
-EMBL Trans Extractor
-Filter DNA
-Filter Protein
-GenBank to FASTA
-GenBank Feature Extractor
-GenBank Trans Extractor
-One to Three
-Range Extractor DNA
-Range Extractor Protein
-Reverse Complement
-Split Codons
-Split FASTA
-Three to One
-Window Extractor DNA
-Window Extractor Protein

Sequence Analysis

-Codon Plot
-Codon Usage
-CpG Islands
-DNA Molecular Weight
-DNA Pattern Find
-DNA Stats
-Fuzzy Search DNA
-Fuzzy Search Protein
-Ident and Sim
-Multi Rev Trans
-Mutate for Digest
-ORF Finder
-Pairwise Align Codons
-Pairwise Align DNA
-Pairwise Align Protein
-PCR Primer Stats
-PCR Products
-Protein GRAVY
-Protein Isoelectric Point
-Protein Molecular Weight
-Protein Pattern Find
-Protein Stats
-Restriction Digest
-Restriction Summary
-Reverse Translate
-Translate

Sequence Figures

-Color Align Conservation
-Color Align Properties
-Group DNA
-Group Protein
-Primer Map
-Restriction Map
-Translation Map

Random Sequences

-Mutate DNA
-Mutate Protein
-Random Coding DNA
-Random DNA Sequence
-Random DNA Regions
-Random Protein Sequence
-Random Protein Regions
-Sample DNA
-Sample Protein
-Shuffle DNA
-Shuffle Protein

Miscellaneous

-IUPAC codes
-Genetic codes
-Browser compatibility
-Mirror this site
-Use this site off-line
-About this site
-Acknowledgments
-Reference

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Sequence Manipulation Suite:

Ident and Sim

Ident and Sim accepts a group of aligned sequences (in FASTA or GDE format) and calculates the identity and similarity of each sequence pair. Identity and similarity values are often used to assess whether or not two sequences share a common ancestor or function.

Paste the aligned sequences in FASTA or GDE format into the text area below. Input limit is 20,000,000 characters.

>CremaneiFEM-2
-------------------MSDSLNHPSSSTVHADDGFEPPTSPEDNNKK
PSLEQIKQEREALFTDLFADRRRSARSVIEEAFQNELMSAEPVQPNVPN-
-PHSIPIRFRHQPVAGPAHDVFGDAVHSIFQKIMSRGVNADYSHWMSYWI
ALGIDKKT-QMNYHMKPFCKDTYATEGSLEAKQTFTDKIRSAVEEIIWKS
AEYCDILSEKWTGIHVSADQLKGQRNKQEDRFVAYPNGQYMNRGQ-SDIS
LLAVFDGHGGHECSQYAAAHFWEAWSDAQHHHSQDMKLDELLEKALETLD
ERMTVRSVRESWKGGTTAVCCAVDLNTNQIAFAWLGDSPGYIMSNLEFRK
FTTEHSPSDPEECRRVEEVGGQIFVIGGELRVNGVLNLTRALGDVPGRPM
ISNKPDTLLKTIEPADYLVLLACDGISDVFNTSDLYNLVQAFVNEYDVED
YHELARYICNQAVSAGSADNVTVVIGFLRPPEDVWRVMKTDSDDEESELE
EEDDNE
>CelegansFEM-2
--------------------------------------------------
--MEKVNEERDAVFEDHIGDRRRSVRSLLEEAFADEMEKTSYDVEVADTP
-QPHIPIRFRHPPIAGPVHDVFGDAIHDIFQKMMKRGQAVDFCHWVSHLI
ATEIDEKFSEVAFRDVQYNPDIYVTDSTTEAKKLFNDKIWPAIDKILQQN
AETCPILSEKWSGIHVSGDQLKGQRHKQEDRFLAYPNGQYMDRGE-DPIS
VLAVFDGHGGHECSQYAAGHLWETWLEVRKSRDPSDSLEDQLRKSLELLD
ERMTVRSVKECWKGGSTAVCCAIDMDQKLMALAWLGDSPGYVMSNIEFRQ
LTRGHSPSDEREARRVEEAGGQLFVIGGELRVNGVLNLTRALGDVPGRPM
ISNEPETCQVPIESSDYLVLLACDGISDVFNERDLYQLVEAFANDYPVED
YAELSRFICTKAIEAGSADNVSVVIGFLRPPQDVWKLMKHESDDEDSDVT
DEE---
>CbriggsaeFEM-2
MSGPPPPKTNEKSSQPVTGRSQEPTRKGQLGPNYLRIIEEDEEYGHALLE
PSEEQIKFEREALFEDLHLDRQRSARSFIEETFEEEMLGPQNGIPPTTES
PQSYIPIRYRNPPAAAPVHDVFGDAVHAIFQKLMTRGPPVEYCHWMSYWI
AKQIDKDS-PVKYHECRFTPDQYVTENTAEAKKTYMDNMWKAAEKNLWMY
TYNSPLLRTKWTGIHVSAEQIKGQRHKQEDRFVAYPNSLYMDTSRSDHIA
LLGVFDGHGGHECSQYAAGHMWETWIETRASHFEEP-LEKQLKTSLDLLD
ERMTVRSTKECWKGGTTAVCCAIDMNKKELAFAWLGDSPGYIMDNLEVRK
VTRDHSPSDPEEGRRVEEAGGQLFVIGGELRVNGVLNLTRALGDVPGRPM
ISNQAETCQRDIEVGDYLVILACDGISDVFNTSDLYNLVQAYVNENPVEE
YNDLAHYICHEAIAHGSTDNVTVVIGFLRPPQDLWRMMKIDEESDEEEDE
VDDE--

Enter the groups of similar amino acids separated by commas to be used for the similarity calculation. If you are comparing DNA sequences, leave this text area empty.

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