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C3 Spacer
The C3 Spacer phosphoramidite can be incorporated internally or at the 3'-end of the oligo. Multiple C3 spacers can be added at the 3'-end of an oligo to introduce a long hydrophilic spacer arm for the attachment of fluorophores or other pendent groups.
|
Position
|
Synthesis Scale [µmol]
|
Purification
|
|||||
|
|
0.04
|
0.2
|
1.0
|
15
|
Des
|
HPLC
|
PAGE
|
| 3' |
X
|
X
|
O |
X
|
X | ||
| Int |
X
|
X
|
O |
X
|
X | ||
X = available/on stock
O = on request
dSpacer (1’,2’-Dideoxyribose)
The 1’,2’-Dideoxyribose modification is used to introduce a stable abasic site within an oligonucleotide.
|
Position
|
Synthesis Scale [µmol]
|
Purification
|
|||||
|
|
0.04
|
0.2
|
1.0
|
15
|
Des
|
HPLC
|
PAGE
|
| Int |
X
|
X
|
O |
X
|
X | ||
X = available/on stock
O = on request